A plus sign next to the number “” means that the information is found within the full scientific study rather than the abstract. If you feel that any of our content is inaccurate, out-of-date, or otherwise questionable, please leave a comment or contact us at that each number in parentheses is a clickable link to peer-reviewed scientific studies. Our goal is to not have a single piece of inaccurate information on this website. They are continually monitored by our internal peer-review process and if we see anyone making material science errors, we don't let them write for us again. Our science team must pass long technical science tests, difficult logical reasoning and reading comprehension tests. Our science team is put through the strictest vetting process in the health industry and we often reject applicants who have written articles for many of the largest health websites that are deemed trustworthy. Our team comprises of trained MDs, PhDs, pharmacists, qualified scientists, and certified health and wellness specialists.Īll of our content is written by scientists and people with a strong science background. We are dedicated to providing the most scientifically valid, unbiased, and comprehensive information on any given topic. We believe that the most accurate information is found directly in the scientific source. The most common adverse experiences occurring with ACTIMMUNE therapy are “flu-like” symptoms such as fever, headache, chills, myalgia, or fatigue, which may decrease in severity as treatment continues, and may be minimized by bedtime administration of ACTIMMUNE.SelfDecode has the strictest sourcing guidelines in the health industry and we almost exclusively link to medically peer-reviewed studies, usually on PubMed.At doses 10 times greater than the weekly recommended dose, ACTIMMUNE may exacerbate pre-existing cardiac conditions, or may cause reversible neurological effects such as decreased mental status, gait disturbance, and dizziness.Reversible neutropenia, thrombocytopenia, and elevations of AST and/or ALT have been observed during ACTIMMUNE therapy.Isolated cases of acute serious hypersensitivity reactions have been observed in patients receiving ACTIMMUNE.Acetaminophen may be used to prevent or partially alleviate the fever and headache The most common adverse experiences occurring with ACTIMMUNE therapy are “flu-like” symptoms such as fever, headache, chills, myalgia, or fatigue, which may decrease in severity as treatment continues, and may be minimized by bedtime administration of ACTIMMUNE.Avoid simultaneous administration of ACTIMMUNE with other heterologous serum protein or immunological preparations (eg, vaccines).Concomitant use of drugs with neurotoxic, hematotoxic, or cardiotoxic effects may increase the toxicity of interferons.Long-term effects of ACTIMMUNE on fertility are not known.ACTIMMUNE or nursing should be discontinued dependent on the importance of the drug to the mother Use of ACTIMMUNE by lactating mothers is not recommended.ACTIMMUNE should be used during pregnancy only if the potential benefit outweighs the potential risk to the fetus.Renal toxicity has been reported in patients receiving ACTIMMUNE Monitor renal function regularly when administering ACTIMMUNE in patients with severe renal insufficiency accumulation of interferon gamma-1b may occur with repeated administration.If severe hepatic enzyme elevations develop, ACTIMMUNE dosage should be modified Patients begun on ACTIMMUNE before age 1 year should receive monthly assessments of liver function.Myelosuppression, or receiving other potentially myelosuppressive agents consider dose reduction or discontinuation of therapy.Seizure disorders or compromised central nervous system function reduce dose or discontinue.Pre-existing cardiac conditions, including ischemia, congestive heart failure, or arrhythmia.ACTIMMUNE should be used with caution in patients with:.coli derived products, or any component of the product In patients who develop or have known hypersensitivity to interferon-gamma, E.IMPORTANT SAFETY INFORMATION CONTRAINDICATIONS For delaying time to disease progression in patients with severe, malignant osteopetrosis.For reducing the frequency and severity of serious infections associated with Chronic Granulomatous Disease.ACTIMMUNE ® (Interferon gamma-1b) is indicated:
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